Composed of 15 amino acids, BPC 157 is a peptide that occurs naturally within the gastric juices of humans (1). It offers gastrointestinal protective qualities and can provide relief from conditions such as ulcers, digestive disturbances, and Crohn’s disease. BPC 157 is considered to have considerable potential in medicinal applications, being a powerful healing agent both when administered via injection or taken orally.
Dubbed as a “miracle agent,” BPC 157 is renowned for its rapid repair and regeneration abilities, likened to those found in the comic book character Wolverine.
Advantages of BPC 157
- Accelerated healing of wounds and tissues
- Reduction in blood pressure levels
- Enhanced muscle repair
- Alleviation of pain
- Decrease in body fat
- Exhibiting certain growth-promoting effects
- Age-reversal properties
- Improvement in overall mood
The wide-ranging benefits of BPC 157 touch upon various aspects including muscles, tendons, the central nervous system (CNS), and inflammatory processes. Aside from its significant impact on wound rehabilitation and tissue repair, particularly with damage linked to corticosteroid use, BPC 157 promotes the formation of new blood vessels, a cardioprotective process known as angiogenesis.
In the realm of bodybuilding, BPC 157 is gaining popularity with both male and female athletes seeking to recover from weightlifting injuries. It also bolsters muscle recuperation, which facilitates more intensive and frequent training while simultaneously minimizing discomfort.
As an anabolic peptide, BPC 157 may encourage fat loss underneath the skin while concurrently promoting muscle growth and strength. BPC 157 is also compared to other growth hormone-enhancing peptides for its ability to stimulate collagen production and demonstrate anti-aging effects.
Pain relief with BPC 157 is notable due to its role in increasing levels of dopamine and serotonin in the brain. Furthermore, the peptide can lessen scar formation, accelerating the body’s natural healing process.
Due to the elevation of these neurotransmitters, BPC 157 displays antidepressant effects, with some patients reporting an improvement in mental clarity and reduction of brain fog.
Possible Side Effects of BPC 157
Despite the scarcity of extensive research on BPC 157, clinical observations have, so far, shown no significant side effects tied to its use.
There are informal, individual testimonials of BPC 157 use extending over years with no evident adverse outcomes (2).
However, certain concerns must be noted. Being a growth factor, BPC 157 promotes tissue growth, similar to growth hormones; hence, it could theoretically worsen conditions in cancer patients, who should avoid using this peptide.
Patients on blood pressure medications should also be cautious as BPC 157 can potentially cause drastic decreases in blood pressure, possibly leading to symptoms like dizziness or fainting if not properly monitored.
Differing from other compounds that boost growth hormone, there is no evidence to suggest BPC 157 raises blood sugar levels, which could contribute to heightened blood pressure.
BPC 157 is not associated with any toxicity toward the liver, kidneys, or heart.
Post-use mood changes may occur as serotonin and dopamine levels tend to spike during BPC 157 cycles, but it’s not confirmed whether these levels promptly normalize after the cycle or if they temporarily surge. Nevertheless, one could assume that neurotransmitter levels would likely stabilize post-cycle due to the peptide’s nature.
Individuals may experience slight headaches as a response to BPC 157 use.
Update: While not widely reported, we have observed a small number of users experiencing histamine responses upon initial BPC 157 dosage. Starting with cautious doses and gradually increasing the dose has proven effective in managing such reactions, allowing the affected individuals to proceed with their regimen.
BPC 157 Recommended Dosage
To date, no official dosage guidelines have been established by medical authorities for BPC 157, as it lacks FDA approval.
Still, users have reported favorable outcomes with dosages of 500–1,000 mcg/day when taken orally, or 400–600 mcg/day when injected subcutaneously near the affected area.
High doses could be split and taken twice daily. Even at lower doses, we’ve observed substantial benefits, suggesting that higher doses might only be necessary in more severe cases.
BPC 157 usage varies from cycling, akin to steroids, to continuous use for several years. More research is required to definitively assess the long-term safety of this peptide; nevertheless, extensive use has not been linked to negative consequences in user accounts.
Reviews of BPC 157
These reviews were compiled from some private steroids forum:
Over the years, I’ve dedicated myself to utilizing peptide therapies including TB 500, BPC 157, Sermorelin, and CJC-1295/Ipamorelin to enhance growth hormone levels and support bodily recovery. Persistent knee and back pain had previously rendered me inactive; I was unable to engage in physical activities or exercise. Initially, navigating the peptide landscape was a daunting task, particularly with regards to finding trustworthy clinics and pharmacies that truly valued patient care over profit. It was a complex process to determine the appropriate dosages, methods of application, and duration for each peptide treatment. However, I eventually recognized the significance of pairing peptide use with proper nutrition and incorporating specific mobility and strength exercises aimed at recovery. Adopting this comprehensive approach not only hastened the healing process but also ensured enduring health improvements. By combining distinct peptides to create a synergistic effect, I saw a significant enhancement in my results. With diligent research and unwavering persistence, I transitioned from being sedentary and plagued by pain to feeling revitalized and achieving optimal physical condition, even into my 40s. The remarkable transformation that peptides have enabled in my life feels nothing short of miraculous. I am excited to share my insights and learn from this community!
After experimenting with a variety of peptides individually, I discovered that a combination approach using BPC-157 and TB-4 had a pronounced effect on my connective tissue ailments. I’ve exclusively used subcutaneous injections, and since then, I’ve experienced a noticeable difference; my hip no longer dislocates. While I’ve come across information suggesting injection location is not crucial, I’ve personally found injecting close to the affected area yields the best results.
Dealing with arthritis in my legs and hips, I’ve been administering injections in those areas and have noted positive results. My ring finger, which was often stiff and would bend uncooperatively, improved substantially after a single injection. It’s been two weeks since that treatment, and I’ve observed no recurrence of the issue.
BPC 157 and Erectile Dysfunction:
Some individuals have experienced immediate enhancements in erectile functionality following the administration of BPC 157, possibly due to an increase in dopamine levels. Dopamine stimulates oxytocin-producing neurons in the PVN, which suggests higher levels could boost sexual performance in males.
Moreover, men with penile injuries, such as those caused by venous leaks, might find benefits with BPC 157 due to its cellular repair and rejuvenation capabilities. An uptick in libido has also been observed by some users, potentially a result of increased dopamine levels.
BPC 157 Pills vs Injectable:
When it comes to using BPC 157, intramuscular injections are most effective for targeting injuries and localized pain. However, oral intake of BPC 157 can still be efficacious in the body’s healing and repair processes, should injections be undesirable.
For issues related to the gastrointestinal system, consuming BPC 157 orally is advised due to its gastroprotective characteristics.
BPC 157 vs TB-500:
Additionally, TB-500 presents itself as a potent healing agent. This peptide is a synthetic form of Thymosin Beta 4, which originates from the thymus gland.
In our experiences, both BPC 157 and TB-500 are comparably effective in healing bones, joints, and connective tissues.
TB-500 is particularly advantageous for enhancing overall strength and muscle growth. On the other hand, BPC 157 stands out for addressing gastrointestinal issues as it is derived from gastric juice.
Both peptides can be utilized together to achieve even better healing outcomes, as they offer different but complementary healing mechanisms.
While TB-500 operates on a systemic level and does not require targeting a specific area, BPC 157 is unique for its localized healing impacts and should be injected near the site of injury.
An optimal dosage for TB-500 would range from 10–20 milligrams weekly, administered once or twice a week for maximum effectiveness.
How legitimate is BPC 157?
BPC 157 is legally available in many nations, including the US, Canada, and the UK, for research usage. This includes applications on animals and observing the resultant effects. Its use in humans remains unauthorized by the FDA due to inadequate clinical validation.
However, as of January 1st, 2022, the World Anti-Doping Agency (WADA) has classified BPC 157 as a banned substance. Athletes should verify with their respective sports authorities regarding testing for BPC 157, particularly during the off-season, as it could be used to expedite injury recovery.
In conclusion
There is a consensus within user-based evidence that BPC 157 provides extensive healing and rejuvenating benefits with minimal side effects.
Although anecdotal accounts suggest BPC 157 is relatively safe with rare adverse reactions, conclusive long-term studies are still needed for FDA endorsement.
REFERENCES
(1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096228/
(2) https://www.youtube.com/watch?v=KBCHy6r3ZAc
(3) https://www.usada.org/spirit-of-sport/education/bpc-157-peptide-prohibited/
Dr. Grant Fourie, a specialist in male hormones, is based in Cape Town, South Africa. He provides comprehensive treatments for conditions related to low testosterone, such as erectile dysfunction, fatigue, and mood changes. His methods include hormone replacement therapy and other modern treatment options.
Contact me via email or phone to book personal appointment in my clinic: The Village Square, Cape Town - South Africa