Explore the top 7 testosterone cycles curated by experts for optimal strength and muscle growth. Dive into the history and evolution of testosterone use since its discovery in 1935. Learn how to safely enhance your performance with detailed cycle guides. Have questions on testosterone cycling? Get professional answers here.
It’s a common belief that with the progression of time, advancements in technology and knowledge bring improvements in product efficacy, including supplements. Nonetheless, this concept does not hold universally true, as evidenced by testosterone, which continues to be one of the most effective steroids available today, per Steroid evaluation.
From our professional assessments, the balance of benefits and potential risks associated with testosterone still ranks it extraordinarily high compared to other anabolic steroids, which is why medical professionals globally are frequently prescribing testosterone replacement therapy (TRT) to a large number of men.
Among those starting their journey into steroids, testosterone is typically the go-to steroid, according to recommendations for beginners. It also serves as a foundational element in more sophisticated steroid regimens.
Upjohn’s lasting impact is evident in their continued production of testosterone nearly 100 years later—now under the corporate identity of Pharmacia & Upjohn.
During the golden age of bodybuilding, testosterone was widely utilized to craft physique legends that, to this day, remain celebrated and upheld as the pinnacle of bodybuilding excellence.
Exploring Various Testosterone Forms
The four leading testosterone esters in popularity are:
- Testosterone Suspension
- Testosterone Propionate
- Testosterone Enanthate
- Testosterone Cypionate (also known as depo-testosterone)
Each ester variant functions as testosterone but differs in its absorption rate and the duration it stays active in the body.
Testosterone Suspension
For newcomers, we advise against using testosterone suspension. Its rapid action, owing to its pure testosterone dissolved in water composition, necessitates twice-daily injections for maintaining optimal serum levels. Some patients report discomfort with suspension injections because they require larger needles to accommodate the non-micronized crystal size.
Testosterone Propionate
When it comes to Testosterone Propionate, its fast-absorbing nature makes it less favorable than other esters, despite its seemingly lower cost. The pricing can be misleading; although Testosterone Propionate is cheaper per milliliter, it is typically dosed at 100mg/mL rather than the standard 250mg/mL. Consequently, the cost of running a standard testosterone cycle with propionate is roughly 2.5 times more expensive, totalling a 50% higher cost compared to other esters. Moreover, the propensity for propionate injections to cause pain leads many to opt for alternate esters.
Testosterone Enanthate and Cypionate
Enanthate and Cypionate, the two leading testosterone forms, consist of longer esters that are slower to become effective. This delayed action means injections are only required once every 4–5 days, while users can still achieve comparable gains by cycle’s end, as they would with faster-acting esters.
In the U.S., Testosterone Cypionate has gained a stronger following than Enanthate due to its relative scarcity worldwide, which has led it to be a domestic favorite. Some users also find that cypionate injections are less irritating than enanthate.
Top 7 Testosterone Cycles
Beginner Testosterone Cycle
Primarily utilizing testosterone cypionate or enanthate
This beginner testosterone cycle, though conservatively dosed, is potent enough to elicit substantial muscle growth and strength enhancements.
A first-time use can yield up to 20 pounds of lean mass gain.
Strength improvements on compound exercises can soar by 30–50lbs, with users breezing past personal bests.
Muscle pumps reach an extraordinary level due to significant increases in intracellular fluid within the muscle cells.
Testosterone’s Side Effects
From our professionals’ experience, testosterone’s safety profile is unrivaled by any other steroid.
Being an injectable steroid, it enters the bloodstream directly, bypassing the liver, and not presenting an obvious risk to hepatic health. Research shows that even 400mg of testosterone administered orally daily has no detrimental impact on liver function after 20 days (1), a finding echoed by our patients’ liver function tests.
In contrast, potent strength-enhancing steroids such as Dianabol or Anadrol in oral form can be harsh on the liver.
In responsible doses, testosterone only causes a mild escalation in LDL cholesterol levels, leading to a moderate elevation in blood pressure—far less than many other steroids that can heavily burden the heart.
Testosterone can induce androgenic side effects, a fact discovered by the Soviet Olympic team that relied on testosterone doping. It provided them a unique upper hand but at the cost of side effects like an enlarged prostate, requiring catheter usage for urination.
Other androgenic side effects are possible, such as oily skin, acne, and hair thinning, with some patients also experiencing increased body or facial hair growth.Individuals with a genetic predisposition may experience gynecomastia as testosterone converts to an estrogen-like substance. It’s also common to observe fluid retention with use.
For individuals faced with gynecomastia, Selective Estrogen Receptor Modulators (SERMs), such as Nolvadex, have proven effective in curbing the enlargement of breast tissue. Nolvadex functions by blocking estrogen in the breast tissue while allowing it to circulate elsewhere, keeping its levels balanced. This approach decreases the chances of gynecomastia while preserving beneficial estrogenic effects on cholesterol and mood.
After discontinuing testosterone, natural production may plummet, leading to a hormonal nadir. Recovery duration varies from 1 to 4 months, influenced by the dosage and cycle length plus the user’s history with steroids. Patients often employ post-cycle therapy (PCT) to hasten the recovery process, which also possesses psychological benefits by restoring a sense of well-being.
Testosterone Cycle Before and After
The initial testosterone cycle at a low dose often results in a bodybuilder dropping fat and accruing significant muscle – about 20 pounds is typical.
Testosterone Cycle (Higher Dose)
| Week | Testosterone |
|---|---|
| 1 | 200mg |
| 2 | 400mg |
| 3 | 400mg |
| 4 | 400mg |
| 5 | 400mg |
| 6 | 500mg |
| 7 | 500mg |
| 8 | 500mg |
| 9 | 500mg |
| 10 | 200mg |
Following initial low-dose cycles, users may escalate to higher dosages for continued muscle and strength gains, potentially adding another 10 pounds of lean muscle.
At these increased dosages, side effects such as heightened post-cycle testosterone suppression and water retention, as well as an escalated risk for gynecomastia, become more pronounced.
Testosterone and Dianabol Cycle
| Week | Testosterone | Dianabol |
|---|---|---|
| 1 | 200mg | — |
| 2 | 400mg | — |
| 3 | 400mg | 10mg/day |
| 4 | 400mg | 10mg/day |
| 5 | 400mg | 20mg/day |
| 6 | 400mg | 20mg/day |
| 7 | 500mg | 30mg/day |
| 8 | 500mg | 30mg/day |
| 9 | 500mg | 30mg/day |
| 10 | 200mg | 30mg/day |
A potent combination for bulking, Dianabol and testosterone team up to provide substantial muscle and strength increases. Dianabol, while less androgenic, surpasses testosterone in its anabolic capabilities.
Testosterone and Dbol Side Effects
This pairing brings a host of potential adverse effects. Oral steroid Dianabol can be harsh on the liver, necessitating liver support supplements to manage enzymes levels.
Despite testosterone’s relative compatibility with cardiovascular health, Dianabol has adverse effects on cholesterol, in part due to its capacity to activate hepatic lipase.
Both compounds can lead to estrogen-related side effects such as gynecomastia, which is high risk with this cycle. A SERM like Nolvadex can assist, excluding its ineffectiveness against fluid retention.
Post-cycle, a robust PCT involving HCG and Clomid is typically required, as testosterone levels can shut down; without it, symptoms of low testosterone might persist for months.
Even with Dianabol’s moderate androgenicity, it, alongside testosterone, can provoke acne and prostate enlargement.
Testosterone and Deca Durabolin Cycle
| Week | Testosterone | Deca Durabolin |
|---|---|---|
| 1 | 600mg | 300mg |
| 2 | 600mg | 300mg |
| 3 | 600mg | 300mg |
| 4 | 600mg | 300mg |
| 5 | 600mg | 300mg |
| 6 | 600mg | 300mg |
| 7 | 600mg | 300mg |
| 8 | 600mg | 300mg |
| 9 | 600mg | 300mg |
| 10 | 600mg | 300mg |
Mixing steroids often intensifies side effects, yet testosterone and Deca Durabolin are exceptions, with minimal impact on the liver and cholesterol levels.
When paired, testosterone and Deca Durabolin can significantly contribute to muscle and strength gains, although Deca exhibits a milder impact as it’s not as potent.
Testosterone and Deca Side Effects
Deca Durabolin is linked to ‘Deca dick,’ an issue where a user may struggle with erections and experience reduced libido. This may be due to Deca’s slight effect on androgen levels and its impact on the body’s own testosterone production.
As Deca is less androgenic, testosterone could be a synergistic partner in a cycle, ensuring DHT levels – which are essential for adequate blood flow to the penis – remain high.Deca Durabolin synergizes effectively with Testosterone due to the need for extended cycle durations and its characteristic as a gradually functioning anabolic steroid.
Conversely, pairing Deca with Anadrol isn’t optimal because Anadrol’s high toxicity limits its usage duration, whereas Testosterone can be safely used over longer periods.
While the risk of developing gynecomastia when using Deca is heightened by its moderate effect on progesterone levels, it is not a common issue for most users. Anecdotal reports suggest that Selective Estrogen Receptor Modulators (SERMs) like Nolvadex might increase progesterone levels when used with Deca. A possible solution is to administer an aromatase inhibitor (AI) like anastrozole to reduce these levels, though AIs can potentially amplify blood pressure issues. Consequently, patients are advised to resort to AIs only if there is noticeable swelling in the nipples.
After completion of a steroid cycle, significant suppression of natural testosterone production is anticipated. To counteract this, a comprehensive Post Cycle Therapy (PCT) regimen consisting of hCG, Nolvadex, and Clomid can be employed to restore endogenous testosterone levels.
Testosterone and Trenbolone Cycles
| Week | Testosterone | Trenbolone |
|---|---|---|
| 1 | 600mg | 150mg |
| 2 | 600mg | 150mg |
| 3 | 600mg | 150mg |
| 4 | 600mg | 150mg |
| 5 | 600mg | 150mg |
| 6 | 600mg | 150mg |
| 7 | 600mg | 150mg |
| 8 | 600mg | 150mg |
| 9 | 600mg | 150mg |
| 10 | 600mg | 150mg |
This combination is highly regarded for bulking, consistently driving substantial increases in both lean muscle tissue and strength. Trenbolone distinguishes itself as a bulking agent that does not aromatize, facilitating a lean and chiseled appearance.
Stacking Testosterone with Trenbolone can rival the sizeable gains achieved with a Testosterone/Dianabol cycle, yet without the associated water weight gain.
Additionally, Trenbolone possesses diuretic effects which contribute to its efficacy during cutting phases. As one of the most sought-after steroids for achieving a robust yet defined physique coupled with enhanced vascularity, Trenbolone remains in high demand.
The stack is particularly potent because of its androgenic profile, leading to significant fat reduction alongside remarkable gains in strength and muscle. This effect on fat loss is associated with increased expression of CPTI (carnitine palmitoyltransferase I) influenced by androgen receptors, which contributes to a decrease in fat mass.
Test and Tren Side Effects
Since Trenbolone, similar to Testosterone, is administered through injections, it does not exert hepatotoxic effects.
The primary concern with Trenbolone use is an increase in blood pressure, resulting from its non-aromatizing nature, which can impact cholesterol levels. Incorporating daily fish oil supplements at 4 grams has been beneficial for some patients in managing blood pressure levels.
Like Deca, Trenbolone displays moderate progesterone activity and could induce gynecomastia. To avoid increasing progesterone levels further, users may wish to avoid SERMs in favor of AIs to prevent gynecomastia. AIs provide protection against both estrogen and progesterone-induced gynecomastia, with the caveat of possible blood pressure escalation. Their use should be limited to instances when early signs of gynecomastia, such as nipple swelling, become apparent.
Commonly used AIs include:
- Anastrozole (Arimidex)
- Exemestane (Aromasin)
- Letrozole (Femara)
Androgenic effects such as hair loss, prostate enlargement, and acne vulgaris are typically observed with Testosterone and Trenbolone cycles due to their highly androgenic nature. The severity of these side effects is largely dependent on individual genetic predispositions. Those with a history of acne or a receding hairline may find that these conditions are exacerbated by this cycle.
To protect against hair loss, some might consider DHT-blocking supplements, which is not recommended due to their potential to diminish muscle gains. This is because DHT is a potent anabolic hormone.
A rigorous PCT protocol including hCG, Nolvadex, and Clomid will be necessary after a Test/Tren cycle to prevent a significant drop-off in hormone levels and to help cement the gains from the cycle.
Testosterone and Anavar Cycles
| Week | Testosterone | Anavar |
|---|---|---|
| 1 | 200mg | 20mg/day |
| 2 | 400mg | 20mg/day |
| 3 | 400mg | 20mg/day |
| 4 | 400mg | 20mg/day |
| 5 | 400mg | 20mg/day |
| 6 | 500mg | 20mg/day |
| 7 | 500mg | 20mg/day |
| 8 | 500mg | 20mg/day |
| 9 | 500mg | — |
| 10 | 200mg | — |
The following cycle is crafted for intermediate users of steroids and involves moderate dosages. In contrast, beginners might opt for a 6-7-week cycle with lower dosages, which would be 350 mg per week of Testosterone and Anavar dosed at 15 mg per day for the first three weeks, then 20 mg per day for the remaining three weeks.
Anavar (Oxandrolone) is considered one of the safest anabolic steroids available, much like Testosterone, and is administered orally.
Recognized primarily as a cutting steroid, Anavar is noted for its pronounced fat-burning capabilities. This effect stems from Anavar’s ability to adjust the T3 to T4 ratio within the body, thereby ramping up metabolic activity and fat burning.
Despite being anabolic, producing observable muscle and strength enhancements, the gains with Anavar are generally less intense when compared to more potent bulking steroids, such as Testosterone.
Although theoretically Anavar is said to be six times more anabolic than Testosterone, from a practical standpoint, this does not often result in greater muscle growth.Consequently, this regimen can serve as a cycle to burn fat while potentially building some lean muscle (when following a calorie-restricted diet).
The virilizing effects of Testosterone can enhance the fat-reducing properties of Anavar, though there might be a temporary increase in water retention.
We have observed that cycles combining Anavar with Testosterone can lead to a considerable accumulation of lean muscle during phases of bulking, all while limiting fat accumulation.
This pairing is considered one of the safest, if not the safest, combinations of steroids for bodybuilders.
Test & Anavar Side Effects
Anavar will exacerbate testosterone suppression after the cycle, necessitating a more sophisticated post-cycle therapy (PCT) than a cycle with only testosterone would. Nonetheless, research indicates that the suppressive effects of Anavar on testosterone are relatively minor compared to those of other anabolic steroids.
Anavar is not prone to aromatization or raising progesterone levels. Therefore, users should not expect any added water retention or gynecomastia, unlike with a cycle using only testosterone.
Anavar is known to alter cholesterol profiles, decreasing HDL and increasing LDL, which could lead to a slight rise in blood pressure (7).
Despite being an oral steroid, Anavar poses minimal risk to the liver because it is metabolized differently, with the kidneys assuming a greater role in processing it.
While androgenic side effects are a possibility with Anavar, the presence of Testosterone means these effects may already be observed.
Testosterone and Anadrol Cycle
| Week | Anadrol | Testosterone |
|---|---|---|
| 1 | 50mg/day | 200mg |
| 2 | 50mg/day | 200mg |
| 3 | 50mg/day | 300mg |
| 4 | 75mg/day | 300mg |
| 5 | 75mg/day | 350mg |
| 6 | 75mg/day | 350mg |
This potent bulking cycle is frequently adopted during the off-season and resembles a Testosterone/Dianabol stack.
For individuals who have previously used testosterone but not Anadrol, this combination can push their muscle size and strength to new heights.
However, Anadrol is notably harsh on the system, being one of the most liver- and heart-straining oral steroids. As a result, while muscle and strength gains may be impressive, the side effects can also be significant.
Note: We’ve observed devastating outcomes in novice users with this cycle (and other Anadrol cycles). Therefore, it should only be undertaken by those with extensive steroid experience.
Testosterone and Anadrol Side Effects
Anadrol dramatically increases levels of AST and ALT enzymes, both indicators of liver strain. Consequently, incorporating liver support is critical when undergoing this cycle.
Tudca has proven to be the most effective supplement for reducing hepatotoxicity in our experience.
High blood pressure is a major concern associated with Anadrol since it promotes hepatic lipase activity and causes substantial fluid retention.
Users are advised to consume 4 grams of fish oil daily, alongside a clean diet and regular cardio exercise, to manage blood pressure. Although often not preferable during a bulking phase, cardio can safeguard heart health, which is appreciated in the long-term.
Anadrol has a significant estrogen-like effect, causing ample water retention and posing a risk of gynecomastia in users. Since it doesn’t convert to estrogen, using an aromatase inhibitor (AI) won’t prevent Anadrol-induced gyno or water retention.
Alternatively, a SERM like Nolvadex can be effective, acting to block estrogen activity in breast tissue (8). This proves a better approach as SERMs don’t contribute to high blood pressure, unlike AIs.
Anadrol also has androgenic effects, increasing the chances of prostate problems, hair loss on the scalp, and acne.
The addition of Anadrol will further suppress natural testosterone production, so post-cycle therapy with Nolvadex, in combination with Clomid and hCG, can help ensure a quick hormonal recovery.
Testosterone / Anadrol / Trenbolone Cycle
| Week | Testosterone | Anadrol | Trenbolone |
|---|---|---|---|
| 1 | 300mg | — | 150mg |
| 2 | 600mg | — | 150mg |
| 3 | 600mg | 50mg | 150mg |
| 4 | 600mg | 50mg | 150mg |
| 5 | 600mg | 100mg | 150mg |
| 6 | 600mg | 100mg | 150mg |
| 7 | 600mg | 100mg | 150mg |
| 8 | 600mg | 100mg | 150mg |
| 9 | 600mg | 100mg | 150mg |
| 10 | 600mg | 100mg | 150mg |
| 11 | 300mg | — | — |
An exceedingly potent blend we’ve seen includes Anadrol, Trenbolone, and Testosterone.
This trio of steroids is regarded as particularly risky, even for veteran bodybuilders, and should be used with extreme caution.
Side effects will likely be more severe than a Testosterone/Anadrol cycle yet may yield greater muscle gains.
Such an intense cycle is generally reserved for IFBB professionals, for whom each pound of muscle is critical for competition.
These bodybuilders, whose placements heavily influence their careers and sponsorship deals, might risk their well-being for the prospect of success.
FAQ
Can I inject Testosterone Subcutaneously?
Based on our experience, testosterone injections are most effective when administered intramuscularly since subcutaneous injections might cause irritation or result in the oil pooling under the skin pending absorption.
It’s advised that users alternate injection sites, which can include the chest, glutes, thigh, lateral deltoids, and trapezius, to minimize discomfort. Additionally, those who find the injection process daunting can opt for esters like cypionate or enanthate that don’t require as frequent injections.
Using a smaller needle gauge, such as 30 or 25, can also offer an injection experience that is less painful and more tolerable.
Overview
Testosterone is known for its capacity to promote muscle growth and support fat loss (9); its anabolic properties are stronger, making it a popular choice for bulking phases.
When considering testosterone esters, it’s unnecessary to venture beyond Enanthate or Cypionate due to their affordability, convenience, and infrequent dosing requirements.
The selection of a specific cycle will depend on the individual’s experience, tolerance levels, and personal goals.
A testosterone-only regimen is recommended for novices, while more seasoned athletes, such as elite bodybuilders who can handle harsher substances, might opt for a testosterone/anadrol combination.
Moreover, those aiming to maintain cardiovascular and hepatic health might pair testosterone with Deca Durabolin or Anavar, steering clear of harsher options like Trenbolone and Anadrol.
Regardless of the chosen cycle, the impact of testosterone on the body will be profound, with significant muscle enlargement and strength gains.
Please Note: Consult with a healthcare professional to ensure the health of your heart and liver before starting testosterone, and keep up with regular medical evaluations throughout your cycle to reduce potential risks.
REFERENCES
(1) https://pubmed.ncbi.nlm.nih.gov/947655/
(3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607063/
(5) https://link.springer.com/article/10.1007/s004310050563
(6) https://pubmed.ncbi.nlm.nih.gov/13894381/
(7) https://academic.oup.com/jcem/article/102/1/176/2804818
Dr. Grant Fourie, a specialist in male hormones, is based in Cape Town, South Africa. He provides comprehensive treatments for conditions related to low testosterone, such as erectile dysfunction, fatigue, and mood changes. His methods include hormone replacement therapy and other modern treatment options.
Contact me via email or phone to book personal appointment in my clinic: The Village Square, Cape Town - South Africa